• Murray K.D., Liu, X.-B., King, A.N., Luu, J. and Cheng, H.-J..  Age-related changes in synaptic plasticity associated with mossy fiber terminal integration during adult neurogenesis.  eNeuro, In press (2020).







  • Chen, S.-Y. and Cheng, H.-J.. Functions of axon guidance molecules in synapse formation. Curr. Opin. Neurobiol. 19:471-478 (2009)
  • Maro, G.S., Shen, K., and Cheng, H.-J.. Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit. Neuron 63:8-11 (2009)


  • Lucanic, M., and Cheng, H.-J.. A RAC/CDC-42 independent GIT/PIX/PAK signaling pathway mediates cell migration in C. elegans. PLoS Genetics 4(11): e1000269 (2008)
  • Schwarz, Q., Waimey, K.E., Golding, M., Takamatsu, H., Kumanogoh, A., Fujisawa, H., Cheng, H.-J., and Ruhrberg, C.. Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development. Developmental Biology 324: 1-9 (2008)
  • Faulkner, R. L., Jang, M.-H., Liu, X.-B., Duan, X., Sailor, K. A., Kim, J. Y., Ge, S., Jones, E. G., Ming, G.-L., Song, H., and Cheng, H.-J.. Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain. Proc. Natl. Acad. Sci. USA 105:14157- 14162 (2008)
  • Faulkner, R. L., Low, L. K., Liu, X.-B., Coble, J., Jones, E. G., and Cheng, H.-J.. Dorsal turning of motor corticospinal axons at the pyramidal decussation requires plexin signaling. Neural Development 3:21 (2008)
  • Low, L. K., Liu, X.-B., Faulkner, R. L., Coble, J., and Cheng, H.-J.. Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex. Proc. Natl. Acad. Sci. USA 105:8136-8141 (2008)
  • Waimey, K.E., Huang, P.-H., Chen, M. and Cheng, H.-J.. Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors. Developmental Biology 315:448-458 (2008)


  • Duan, X., Chang, J. H., Ge, S., Faulkner, R. L., Kim, J. Y., Kitabatake, Y., Liu, X.-b., Yang C.-H., Jordan, J. D., Ma, D. K., Liu, C. Y., Ganesan, S., Cheng, H.-J., Ming, G.-l., Lu, B., and Song, H. Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell 130:1146-1158 (2007)
  • Chung, L., Yang, T.-L., Huang, H.-R., Hsu, S.-M., Cheng, H.-J., and Huang, P.-H.. Semaphorin signaling facilitates cleft formation in the developing salivary gland. Development 134:2935-2945 (2007)
  • Faulkner, R. L., Low, L. K. and Cheng, H.-J.. Axonal pruning in the developing vertebrate hippocampus. Developmental Neuroscience 29:6-13 (2007)


  • Lucanic, M., Kiley, M., Ashcroft, N., LEtoile, N. and Cheng H.-J.. The C. elegans p21 activated kinases are differentially required for UNC-6/Netrin mediated commissural motor axon guidance. Development 133:4549-4559 (2006)
  • Waimey, K. E. and Cheng, H.-J.. Axon pruning and synaptic development: how are they per-plexin? The Neuroscientist 12:398-409 (2006)
  • Low, L. K. and Cheng, H.-J.. Axon pruning: an essential step underlying the developmental plasticity of neuronal connections. Phil. Trans. R. Soc. B 361:1531-1544 (2006)


  • Liu, X.-B., Low, L. K., Jones, E. G., and Cheng, H.-J.. Stereotyped Axon Pruning via Plexin Signaling is Associated with Synaptic Complex Elimination in the Hippocampus. J. Neurosci. 25:9124-9134 (2005)
  • Low, L. K., and Cheng, H.-J.. A little nip and tuck: axon refinement during development and axonal injury. Curr. Opin. Neurobiol. 15:549-556 (2005)
  • Yaron, A, , Huang, P.-H., Cheng, H.-J.*, and Tessier-Lavigne, M.*. Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins. Neuron 45:513-523 (2005) (*co-senior authors)


  • Bagri, A. *, Cheng, H.-J. *, Yaron, A., Pleasure, S. J., and Tessier-Lavigne, M.. Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the Semaphorin family. Cell 113: 285-299. (2003) (*equal contributions)


  • Huang, X., Cheng, H.-J., Tessier-Lavigne, M., Jin, Y.. Max-1, a novel PH/Myth4/FERM domain cytoplasmic protein implicated in netrin-mediated axon repulsion. Neuron 34: 563-76 (2002)


  • Cheng, H.-J.*, Bagri, A.*, Yaron, A., Stein, E., Pleasure, S. J., and Tessier-Lavigne, M.. Plexin-A3 Mediates Semaphorin Signaling and Regulates the Development of Hippocampal Axonal Projections. Neuron 32:249-63. (2001) (*equal contributions)
  • Cheng, H.-J. and Flanagan, J. G.. Cloning and characterization of RTK ligands using receptor-alkaline phosphatase fusion proteins. Methods Mol. Biol. 124: 313-34. (2001)


  • Flanagan, J. G., Cheng, H.-J., Feldheim, D. A., Hattori, M., Lu, Q., Vanderhaeghen, P..  Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos.  Methods Enzymol. 327: 19-35.  (2000)

  • Flanagan, J. G. and Cheng, H.-J..  Alkaline phosphatase fusion proteins for molecular characterization and cloning of receptors and their ligands.  Methods Enzymol. 327: 198-210.  (2000)


  • Nakamoto, M.*, Cheng, H.-J.*, Friedman, G. C., McLaughlin, T., Hansen, M. J., Yoon, C. H., O’Leary, D. D. M. and Flanagan, J. G.. Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Cell 86:755-766 . (1996) (*equal contributions)


  • Cheng, H.-J., Nakamoto, M., Bergemann, A. D. and Flanagan, J. G.. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell 82:371-381. (1995)
  • Bergemann, A. D., Cheng, H.-J., Brambilla, R., Klein, R. and Flanagan, J. G..  ELF-2, a new member of the Eph ligand family, is segmentally expressed in the mouse embryo in the region of the hindbrain and newly forming somites.  Molecular and Cellular Biology 15:4921-4929.  (1995)


  • Cheng, H.-J. and Flanagan. J.G.. Identification and cloning of ELF-1, a developmentally-expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell 79:157-168. (1994)
  • Cheng, H.-J. and Flanagan, J. G..  Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site determined by spacing from the membrane.  Molecular Biology of the Cell 5: 943-953.  (1994)


  • Chuang, P.-T., Cheng, H.-J., Lin, S.-J., Jan, K.-M., Lee, M.-M. and Chien, S..  Macromolecular transport across arterial and venous endothelium in rats, studies with Evan blue-albumin and horseradish peroxidase.  Arteriosclerosis 10:188-197.  (1990)